question: Can women with insulin-dependent diabetes reduce their risk of having children with birth defects?
Women who have insulin-dependent diabetes at the time they become pregnant have a two-to-three times greater risk of having malformed babies than other women. These malformations can affect the central nervous system, heart, kidneys and other organs. Unfortunately, the biochemical mechanisms or causes of such malformations are not yet known. But practically speaking, the risk of malformations can be reduced considerably with good metabolic control prior to the time the embryo's organs start developing. So if a woman with insulin-dependent diabetes has her blood sugar well-controlled before she gets pregnant, her risk of delivering a malformed baby as well as miscarriage is much, much lower.
source :An Interview with James L. Mills, M.D.,ificinfo.health.org
Women who have insulin-dependent diabetes at the time they become pregnant have a two-to-three times greater risk of having malformed babies than other women. These malformations can affect the central nervous system, heart, kidneys and other organs. Unfortunately, the biochemical mechanisms or causes of such malformations are not yet known. But practically speaking, the risk of malformations can be reduced considerably with good metabolic control prior to the time the embryo's organs start developing. So if a woman with insulin-dependent diabetes has her blood sugar well-controlled before she gets pregnant, her risk of delivering a malformed baby as well as miscarriage is much, much lower.
source :An Interview with James L. Mills, M.D.,ificinfo.health.org
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